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PIEZO1 mediates a mechanothrombotic pathway in diabetes

PIEZO1 mediates a mechanothrombotic pathway in diabetes

Thrombosis is the leading cause of death worldwide. Patients with diabetes are at increased risk of thrombosis. Zhu et al., showed that hematopoietic cell selection mediated by the mechanosensitive ion channel Piezo1 drives a novel thrombotic pathway in diabetes, providing a potential therapeutic strategy for thrombotic disease without bleeding complications. Read More
Using artificial intelligence to detect cardiac amyloidosis

Using artificial intelligence to detect cardiac amyloidosis

Artificial intelligence-enabled fully automated detection of cardiac amyloidosis using electrocardiograms and echocardiograms. Read More
Moving Genomics to Routine Care

Moving Genomics to Routine Care

Moving genomics to routine care, which is at the core of One Brave Idea. Read More
Phenotype Phorum 11.6: Roberto Calle, Arun Sanyal, MD & Tania Kamphaus, PhD

Phenotype Phorum 11.6: Roberto Calle, Arun Sanyal, MD & Tania Kamphaus, PhD

One Brave Idea is interested in a variety of scalable traditional and non-traditional phenotypes as entry points into new biology, Read More
Phenotype Phorum 9.26: Bob Tepper, M.D.

Phenotype Phorum 9.26: Bob Tepper, M.D.

Robert Tepper, MD PhD, has catalyzed innovation throughout his career as a physician scientist, biotech R&D leader and most recently Read More
Phenotype Phorum 5.30: Dennis Ausiello & David Edwards

Phenotype Phorum 5.30: Dennis Ausiello & David Edwards

The One Brave Idea Phenotype Phorum welcomed Dr. Dennis Ausiello and Prof. David Edwards recently for a discussion on olfactory Read More
Phenotype Phorum 4.17: Daphne Zohar & Jim Harper

Phenotype Phorum 4.17: Daphne Zohar & Jim Harper

Recently, One Brave Idea welcomed Daphne Zohar, founder and CEO of PureTech Health, and Jim Harper, founder of Sonde Health, Read More
Dr. Calum MacRae to Become Senior Advisor to BioSymetrics

Dr. Calum MacRae to Become Senior Advisor to BioSymetrics

BioSymetrics, an artificial intelligence and machine learning SaaS company, announces Dr. Calum MacRae as Senior Advisor.  Dr. MacRae is an innovative pioneer in genetics, biology, and drug discovery. Read More
National Wear Red Day

National Wear Red Day

Nearly 80 percent of cardiac events can be prevented, but cardiovascular diseases continue to be a woman's greatest health threat. Read More
Phenotype Phorum | Shaun Coughlin

Phenotype Phorum | Shaun Coughlin

We are committed to bringing together diverse groups of scientists to build a community that embraces meaningful collaborations and forums across academia, industry, and medicine. Read More
Quest Diagnostics™ to accelerate cardiovascular disease biomarker

Quest Diagnostics™ to accelerate cardiovascular disease biomarker

Quest Diagnostics will contribute biomarker implementation, population health analytics and a national lab platform as a pillar supporter of One Brave Idea. Read More
PuzzlePieces_Abstract

Real World Evidence And The Collision Between Pharma R&D And Healthcare

By Calum MacRae, M.D., Ph.D., One Brave Idea and Harvard Medical School The true effect of an intervention is often Read More
Well Connected EP 0108, Calum MacRae, MD

Well Connected EP 0108, Calum MacRae, MD

Download file | Play in new window | Duration: 00:39:54Subscribe: iTunes | Stitcher | Google Play Episode 108 brings a Read More
Boston researcher leads initiative to stop coronary heart disease

Boston researcher leads initiative to stop coronary heart disease

Heart disease is the leading cause of death in the United States. There have been advances in treatment and prevention, Read More
American Heart Association, Verily and AstraZeneca Launch One Brave Idea Science Innovation Center

American Heart Association, Verily and AstraZeneca Launch One Brave Idea Science Innovation Center

Boston facility will provide testing ground for researchers to collaborate on “early warning system” for coronary heart disease October 20, Read More
Innovation center with goal of preventing CHD opens

Innovation center with goal of preventing CHD opens

The American Heart Association, Verily and AstraZeneca announced the opening of the One Brave Idea Science Innovation Center in Boston, Read More
One $75 Million Idea To Fight Heart Disease: Earlier Warning Systems

One $75 Million Idea To Fight Heart Disease: Earlier Warning Systems

This week's grand opening of the One Brave Idea research center showcased a splashy, $75 million science project that brings Read More
‘One Brave Idea’ Science Innovation Center Opens in Boston

‘One Brave Idea’ Science Innovation Center Opens in Boston

One Brave Idea is a $75 million research enterprise bringing together scientists from multiple disciplines to to better understand the Read More
AHA CEO Nancy Brown (in red), Greg Keenan of AstraZeneca, Andy Conrad of Verily and One Brave Idea leader Calum MacRae cut the ribbon on the One Brave Idea Science Innovation Center.

One Brave Idea settles into new home

By AMERICAN HEART ASSOCIATION NEWS AHA CEO Nancy Brown (in red), Greg Keenan of AstraZeneca, Andy Conrad of Verily and Read More
The One Brave Idea™ Science Innovation Center opens in Boston

The One Brave Idea™ Science Innovation Center opens in Boston

October 03, 2017 Categories: Program News Boston, MA, October 3, 2017 — The American Heart Association, Verily and AstraZeneca, today Read More
Calum MacRae runs the new research enterprise.

One Brave Idea Science Innovation Center Opens Tomorrow in Boston

One Brave Idea Science Innovation Center Opens Tomorrow in Boston By HEATHER GOLDSTONE & ELSA PARTAN • OCT 2, 2017 Read More
Get Social with OBI

Get Social with OBI

Our goal is to revolutionize the way people get and stay healthy by launching innovations to solve coronary heart disease. Follow the official One Brave Idea™ twitter page to stay up-to-date with content! Read More
Scientist using big data against heart disease wins $75 million award

Scientist using big data against heart disease wins $75 million award

Scientist using big data against heart disease wins $75 million award By SHARON BEGLEY @sxbegle OCTOBER 5, 2016 JEAN-SEBASTIEN EVRARD/AFP/GETTY Read More
Calum MacRae headshot

Calum MacRae receives $75 million to pursue ‘One Brave Idea’ to beat coronary heart disease

By AMERICAN HEART ASSOCIATION NEWS After 25 years of conducting scientific research and treating patients, Dr. Calum MacRae was frustrated Read More
American Heart Association, Verily Life Sciences and AstraZeneca Announce Winner of Innovative $75M One Brave Idea Research Award

American Heart Association, Verily Life Sciences and AstraZeneca Announce Winner of Innovative $75M One Brave Idea Research Award

Virtual Press Conference via YouTube Live Scheduled for Today, October 5, 2016 at 2:30pm ET/11:30 am PT October 05, 2016 Read More