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PIEZO1 mediates a mechanothrombotic pathway in diabetes

Thrombosis is the leading cause of death worldwide. Patients with diabetes are at increased risk of thrombosis. Zhu et al., showed that hematopoietic cell selection mediated by the mechanosensitive ion channel Piezo1 drives a novel thrombotic pathway in diabetes, providing a potential therapeutic strategy for thrombotic disease without bleeding complications.
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Using artificial intelligence to detect cardiac amyloidosis

Artificial intelligence-enabled fully automated detection of cardiac amyloidosis using electrocardiograms and echocardiograms.
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Moving Genomics to Routine Care

Moving genomics to routine care, which is at the core of One Brave Idea.
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Phenotype Phorum 11.6: Roberto Calle, Arun Sanyal, MD & Tania Kamphaus, PhD

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The One Brave Idea Team comprises a group of investigators across a wide variety of disciplines—such as cardiology, data science, and engineering—and institutions including MIT and Stanford.

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  • About
    • About Us
    • About The Award
  • Team
    • Our Team
    • Executive Management and Operations
    • Joint Leadership
    • Scientific Staff
  • Our Approach
    • Our Approach
    • Deep Phenotyping
    • Early Detection
    • Engaging Broad Patient Populations in Research
    • Genomics + Phenotyping in Clinical Care
    • Integrative Computational Research
    • Promoting Non-Traditional Partnerships
  • News
  • Events
  • Careers
  • Education & Training
    • Mower Fellowship
      • Meet the Mower Fellows
    • iD2D
      • Innovating in the 21st Century: What’s New?
      • Program Teasers
      • Development Team
      • Participant Testimonials
  • Contact